{"id":1422,"date":"2026-02-03T14:15:11","date_gmt":"2026-02-03T19:15:11","guid":{"rendered":"https:\/\/groups.chem.cmu.edu\/ly\/?page_id=1422"},"modified":"2026-06-28T23:56:50","modified_gmt":"2026-06-29T03:56:50","slug":"home-2","status":"publish","type":"page","link":"https:\/\/groups.chem.cmu.edu\/ly\/","title":{"rendered":"Home"},"content":{"rendered":"<div class=\"et_pb_section_0 et_pb_section et_section_specialty et_pb_equal_columns et_pb_gutters3 et_block_section\"><div class=\"et_pb_row et_pb_row-1-4_3-4 et_block_row\">\n<div class=\"et_pb_column_0 et_pb_column et_pb_column_single et_pb_column_1_4 et_block_column et_pb_css_mix_blend_mode_passthrough\">\n<div class=\"et_pb_text_0 et_pb_text et_pb_bg_layout_light et_pb_module et_block_module\"><div class=\"et_pb_text_inner\"><h3 style=\"text-align: right\">Department of Chemistry<\/h3>\n<p style=\"text-align: right\">Carnegie Mellon University<\/p>\n<\/div><\/div>\n<\/div>\n\n<div class=\"et_pb_column_1 et_pb_column et_pb_specialty_column et_pb_column_3_4 et-last-child et_block_column et_pb_css_mix_blend_mode_passthrough\">\n<div class=\"et_pb_row_inner_0 et_pb_row_inner et_block_row\">\n<div class=\"et_pb_column_inner_0 et_pb_column_inner et_pb_column et_pb_column_4_4 et-last-child et_block_column et_pb_css_mix_blend_mode_passthrough\">\n<div class=\"et_pb_heading_0 et_pb_heading et_pb_module et_block_module\"><div class=\"et_pb_heading_container\"><h1 class=\"et_pb_module_header\">The Ly Group<\/h1><\/div><\/div>\n\n<div class=\"et_pb_image_0 et_pb_image et_pb_module et_block_module\"><span class=\"et_pb_image_wrap\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/groups.chem.cmu.edu\/ly\/wp-content\/uploads\/sites\/7\/2019\/09\/cropped-55e3dd414f52ab14ea89837cc3202a7f1039d7e35357714171_1920.jpg\" width=\"1920\" height=\"1079\" srcset=\"https:\/\/groups.chem.cmu.edu\/ly\/wp-content\/uploads\/sites\/7\/2019\/09\/cropped-55e3dd414f52ab14ea89837cc3202a7f1039d7e35357714171_1920.jpg 1920w, https:\/\/groups.chem.cmu.edu\/ly\/wp-content\/uploads\/sites\/7\/2019\/09\/cropped-55e3dd414f52ab14ea89837cc3202a7f1039d7e35357714171_1920-300x169.jpg 300w, https:\/\/groups.chem.cmu.edu\/ly\/wp-content\/uploads\/sites\/7\/2019\/09\/cropped-55e3dd414f52ab14ea89837cc3202a7f1039d7e35357714171_1920-768x432.jpg 768w, https:\/\/groups.chem.cmu.edu\/ly\/wp-content\/uploads\/sites\/7\/2019\/09\/cropped-55e3dd414f52ab14ea89837cc3202a7f1039d7e35357714171_1920-1024x575.jpg 1024w, https:\/\/groups.chem.cmu.edu\/ly\/wp-content\/uploads\/sites\/7\/2019\/09\/cropped-55e3dd414f52ab14ea89837cc3202a7f1039d7e35357714171_1920-940x529.jpg 940w\" sizes=\"(max-width: 1920px) 100vw, 1920px\" class=\"wp-image-234\" title=\"cropped-55e3dd414f52ab14ea89837cc3202a7f1039d7e35357714171_1920.jpg\" \/><\/span><\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div><\/div>\n\n<div class=\"et_pb_section_1 et_pb_section et_section_regular et_block_section\">\n<div class=\"et_pb_row_0 et_pb_row et_block_row\">\n<div class=\"et_pb_column_2 et_pb_column et_pb_column_4_4 et-last-child et_block_column et_pb_css_mix_blend_mode_passthrough\">\n<div class=\"et_pb_text_1 et_pb_text et_pb_bg_layout_light et_pb_module et_block_module\"><div class=\"et_pb_text_inner\"><p style=\"text-align: justify\">Our research program has been focused on the design and development of molecular tools and reagents to regulate gene expression and probe protein localization and dynamics in human somatic and embryonic stem (ES) cells. We are particularly interested in dissecting the genetic blueprint of human ESC and addressing fundamental questions pertaining to the cellular origins of cancer. More recently, we have expanded our research program into other areas including protein design, tissue engineering and molecular self-assembly\u2014taking advantage of the strength of the department, which is interdisciplinary research, combined with our ability to synthesize molecules that integrate all three features of the natural biopolymers: nucleic acids, proteins, and carbohydrates.<\/p>\n<\/div><\/div>\n<\/div>\n<\/div>\n<\/div>\n\n<div class=\"et_pb_section_2 et_pb_section et_section_regular et_block_section\">\n<div class=\"et_pb_row_1 et_pb_row et_pb_equal_columns et_block_row\">\n<div class=\"et_pb_column_3 et_pb_column et_pb_column_1_2 et_block_column et_pb_css_mix_blend_mode_passthrough\">\n<div class=\"et_pb_text_2 et_pb_text et_pb_bg_layout_light et_pb_module et_block_module\"><div class=\"et_pb_text_inner\"><h3 class=\"widget-title\">Recent News<\/h3>\n<p>\u27a4 <a href=\"https:\/\/basebybase.castos.com\/episodes\/pothole-filling-rcug-gamma-pna\" target=\"_blank\" rel=\"noopener\">Bifacial \u03b3PNA triplets target rCUG repeats and displace MBNL1 in Myotonic Dystrophy type 1<\/a><span>, Base by Base Podcast, January 18, 2026<\/span><\/p>\n<p><span>\u27a4 <a href=\"https:\/\/www.cmu.edu\/news\/stories\/archives\/2026\/january\/breakthrough-in-rna-research-could-lead-to-treatment-for-neuromuscular-disorders?utm_campaign=2026-01-15+Piper&amp;utm_source=headr&amp;utm_medium=all&amp;utm_content=res_sci_0&amp;utm_term=mcs_0&amp;utm_id=Breakthrough+in+RNA+Research+Could+Lead+to+Treatment+for+Neuromuscular+Disorders\" target=\"_blank\" rel=\"noopener\">Breakthrough in RNA Research Could Lead to Treatment for Neuromuscular Disorders<\/a>, Mellon College of Science News, January 15, 2026<\/span><\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<\/div><\/div>\n<\/div>\n\n<div class=\"et_pb_column_4 et_pb_column et_pb_column_1_2 et-last-child et_block_column et_pb_css_mix_blend_mode_passthrough\">\n<div class=\"et_pb_contact_form_0 et_pb_contact_form_container 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